Dermatitis herpetiformis: specific manifestation of celiac disease
dc.creator | Correa Parra, Laura | |
dc.creator | Villa Saldarriaga , Maria Paulina | |
dc.creator | Forero Saldarriaga, Santiago | |
dc.date | 2021-10-29 | |
dc.date.accessioned | 2024-09-12T00:54:03Z | |
dc.date.available | 2024-09-12T00:54:03Z | |
dc.description | Celiac disease is a systemic disorder with an autoimmune basis, secondary to continuous exposure to gluten in people with genetic susceptibility, which leads to the development of specific antibodies mainly affecting the small intestine with subsequent enteropathy. The clinical manifestations include digestive symptoms and extra intestinal manifestations. In this last group, the dermatological manifestations stand out, specifically dermatitis herpetiformis, which is considered specific to Celiac disease. It presents clinically as a pruritic papulovesicular rash. The diagnosis is based on a skin biopsy with direct immunofluorescence and the presence of anti-tissue transglutaminase 2 antibodies, only in specific cases it should be complemented with other studies. Treatment is based on a gluten-free diet, which improves symptoms, controls and prevents complications of Celiac disease, such as digestive neoplasms and the development of other autoimmune diseases. | en-US |
dc.description | La enfermedad celíaca es un trastorno sistémico con base autoinmune, secundario a la exposición continua al gluten en personas con susceptibilidad genética, que lleva a desarrollo de anticuerpos específicos, afectando principalmente el intestino delgado con la subsecuente enteropatía. Las manifestaciones clínicas incluyen síntomas digestivos y manifestaciones extra intestinales. En este último grupo se destacan las manifestaciones dermatológicas, específicamente la dermatitis herpetiforme, la cual es considerada específica de la enfermedad celíaca. Clínicamente, se presenta como un exantema papulovesicular pruriginoso. El diagnóstico se basa en la biopsia de piel con inmunofluorescencia directa y la presencia de anticuerpos anti-transglutaminasa tisular 2 y solo en casos específicos se debe complementar con otros estudios. El tratamiento se basa en dieta libre de gluten, que mejora la sintomatología, controla y previene las complicaciones de la enfermedad celíaca, como las neoplasias digestivas y el desarrollo de otras enfermedades autoinmunes. | es-ES |
dc.format | application/pdf | |
dc.identifier | https://revistas.ces.edu.co/index.php/medicina/article/view/6352 | |
dc.identifier.uri | https://ciencianacional.co/handle/123456789/208151 | |
dc.journal | CES Medicina | |
dc.language | spa | |
dc.publisher | Universidad CES | es-ES |
dc.relation | https://revistas.ces.edu.co/index.php/medicina/article/view/6352/3504 | |
dc.relation | /*ref*/Rubin JE, Crowe SE. Celiac Disease. Ann Intern Med. 2020;172(1): ITC1-16. DOI: 10.7326/AITC202001070 | |
dc.relation | /*ref*/Bureš J. History of celiac disease. Vnitr Lek. 2018;64(6):600-1. URL: https://pubmed.ncbi.nlm.nih.gov/30223657/ | |
dc.relation | /*ref*/Yu XB, Uhde M, Green PH, Alaedini A. Autoantibodies in the Extraintestinal Manifestations of Celiac Disease. Nutrients. 2018;10(8): E1123. DOI: 10.3390/nu10081123 | |
dc.relation | /*ref*/Parra-Medina R, Molano-Gonzalez N, Rojas-Villarraga A, Agmon-Levin N, Arango M-T, Shoenfeld Y, et al. Prevalence of Celiac Disease in Latin America: A Systematic Review and Meta-Regression. PLOS ONE. 2015;10(5): e0124040. DOI: 10.1371/journal.pone.0124040 | |
dc.relation | /*ref*/Therrien A, Kelly CP, Silvester JA. Celiac Disease: Extraintestinal Manifestations and Associated Conditions. J Clin Gastroenterol. 2020;54(1): 8-21. DOI: 10.1097/MCG.0000000000001267 | |
dc.relation | /*ref*/Abenavoli L, Dastoli S, Bennardo L, Boccuto L, Passante M, Silvestri M, et al. The Skin in Celiac Disease Patients: The Other Side of the Coin. Medicina (Mex). 2019;55(9): 578. DOI: 10.3390/medicina55090578 | |
dc.relation | /*ref*/Leffler DA, Green PHR, Fasano A. Extraintestinal manifestations of coeliac disease. Nat Rev Gastroenterol Hepatol. 2015;12(10): 561-71. DOI: 10.1038/nrgastro.2015.131 | |
dc.relation | /*ref*/Lebwohl B, Sanders DS, Green PHR. Coeliac disease. Lancet Lond Engl. 2018;391(10115): 70-81. | |
dc.relation | /*ref*/Antiga E, Maglie R, Quintarelli L, Verdelli A, Bonciani D, Bonciolini V, et al. Dermatitis Herpetiformis: Novel Perspectives. Front Immunol. 2019;10: 1290. DOI: 10.3389/fimmu.2019.01290 | |
dc.relation | /*ref*/Salmi TT. Dermatitis herpetiformis. Clin Exp Dermatol. 2019;44(7): 728-31. DOI: 10.1111/ced.13992 | |
dc.relation | /*ref*/Sanjinés DL. Dermatitis herpetiforme como carta de presentación de la enfermedad celíaca. Rev Urug Med Interna. 2016;7. URL: http://www.scielo.edu.uy/pdf/rumi/v1n1/v1n1a03.pdf | |
dc.relation | /*ref*/J. FM, P. RQ. Enfermedad celiaca: Revisión. Rev Médica Clínica Las Condes. 2015;26(5): 613-27. | |
dc.relation | /*ref*/Rojas-Vargas C. Enfermedad celíaca: una enfermedad autoinmune. Rev Médica Sinerg. 2021;6: 11. DOI: 10.1016/j.rmclc.2015.09.007 | |
dc.relation | /*ref*/Jericho H, Sansotta N, Guandalini S. Extraintestinal Manifestations of Celiac Disease: Effectiveness of the Gluten-Free Diet. J Pediatr Gastroenterol Nutr. 2017;65(1):75-9. DOI: 10.1097/MPG.0000000000001420 | |
dc.relation | /*ref*/Muddasani S, Rusk AM, Baquerizo Nole KL. Gluten and skin disease beyond dermatitis herpetiformis: a review. Int J Dermatol. 2021;60(3):281-8. DOI: 10.1111/ijd.15098 | |
dc.relation | /*ref*/Salmi TT, Hervonen K, Kautiainen H, Collin P, Reunala T. Prevalence and incidence of dermatitis herpetiformis: a 40-year prospective study from Finland. Br J Dermatol. 2011;165(2): 354-9. DOI: 10.1111/j.1365-2133.2011.10385.x | |
dc.relation | /*ref*/Mansikka E, Hervonen K, Kaukinen K, Collin P, Huhtala H, Reunala T, et al. Prognosis of Dermatitis Herpetiformis Patients with and without Villous Atrophy at Diagnosis. Nutrients. 2018;10(5): E641. DOI: 10.3390/nu10050641 | |
dc.relation | /*ref*/Lindfors K, Ciacci C, Kurppa K, Lundin KEA, Makharia GK, Mearin ML, et al. Coeliac disease. Nat Rev Dis Primer. 2019;5(1): 3. | |
dc.relation | /*ref*/Leffler DA, Schuppan D. Update on serologic testing in celiac disease. Am J Gastroenterol. 2010;105(12):2520-4. | |
dc.relation | /*ref*/Pallav K, Kabbani T, Tariq S, Vanga R, Kelly CP, Leffler DA. Clinical Utility of Celiac Disease-Associated HLA Testing. Dig Dis Sci. 2014;59(9): 2199-206. DOI: 10.1038/s41572-018-0054-z | |
dc.relation | /*ref*/Ludvigsson JF, Bai JC, Biagi F, Card TR, Ciacci C, Ciclitira PJ, et al. Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology. Gut. 2014;63(8): 1210-28. DOI: 10.1136/gutjnl-2013-306578 | |
dc.relation | /*ref*/Downey L, Houten R, Murch S, Longson D, Guideline Development Group. Recognition, assessment, and management of coeliac disease: summary of updated NICE guidance. BMJ. 2015;351:h4513. | |
dc.relation | /*ref*/Antiga E, Caproni M. The diagnosis and treatment of dermatitis herpetiformis. Clin Cosmet Investig Dermatol. 2015;8:257-65. DOI: 10.2147/CCID.S69127 | |
dc.relation | /*ref*/Rodrigo L, Beteta-Gorriti V, Alvarez N, Gómez de Castro C, de Dios A, Palacios L, et al. Cutaneous and Mucosal Manifestations Associated with Celiac Disease. Nutrients. 2018;10(7):E800. DOI: 10.3390/nu10070800 | |
dc.relation | /*ref*/Baptista A, Madanelo S, Morais P. A pruritic vesicular rash. Aust Fam Physician. 2017;46(1):45-7. | |
dc.relation | /*ref*/Syage JA, Green PHR, Khosla C, Adelman DC, Sealey-Voyksner JA, Murray JA. Latiglutenase Treatment for Celiac Disease: Symptom and Quality of Life Improvement for Seropositive Patients on a Gluten-Free Diet. GastroHep. 2019;1(6):293-301. DOI: 10.1002/ygh2.371 | |
dc.relation | /*ref*/Ja M, Cp K, Phr G, A M, Tt W, M M, et al. No Difference Between Latiglutenase and Placebo in Reducing Villous Atrophy or Improving Symptoms in Patients With Symptomatic Celiac Disease. Gastroenterology. 2021];152(4). URL:https://pubmed.ncbi.nlm.nih.gov/27864127/ | |
dc.relation | /*ref*/Zingone F, Abdul Sultan A, Crooks CJ, Tata LJ, Ciacci C, West J. The risk of community-acquired pneumonia among 9803 patients with coeliac disease compared to the general population: a cohort study. Aliment Pharmacol Ther. 2016;44(1):57-67. DOI: 10.1111/apt.13652 | |
dc.relation.institution | Universidad CES | |
dc.rights | Derechos de autor 2021 CES Medicina | es-ES |
dc.rights | https://creativecommons.org/licenses/by-nc-sa/4.0 | es-ES |
dc.source | CES Medicina; Vol. 35 Núm. 3 (2021): CES Medicina ; 272-283 | es-ES |
dc.source | 2215-9177 | |
dc.source | 0120-8705 | |
dc.subject | celiac disease | en-US |
dc.subject | skin diseases | en-US |
dc.subject | dermatitis herpetiformis | en-US |
dc.subject | diet | en-US |
dc.subject | gluten-free | en-US |
dc.subject | enfermedad celíaca | es-ES |
dc.subject | enfermedades de la piel | es-ES |
dc.subject | dermatitis herpetiforme | es-ES |
dc.subject | dieta sin gluten | es-ES |
dc.title | Dermatitis herpetiformis: specific manifestation of celiac disease | en-US |
dc.title | Dermatitis herpetiforme: manifestación específica de la enfermedad celiaca | es-ES |
dc.type | info:eu-repo/semantics/article | |
dc.type | info:eu-repo/semantics/publishedVersion |