Currently, cosmetics producers in Colombia are facing an increasingly competitive and demanding environment; on the one hand, to market their products in national territory and countries of the Andean Community of Nations they must implement and comply with the provisions in the legislation, Decision 516 of 2002 and Resolution 3773 of 2004, but if they wish to reach the countries of the European Community they must comply with the Good Manufacturing Practices (ISO 22716:2007). Cosmetic producers can voluntarily certify with the health authority, INVIMA, the Good Manufacturing Practices through Resolution 3774 of 2004 or with a certifying body the ISO 22716:2007. This is the panorama of the cosmetics sector in Colombia, which, in response to the competitive environment, implements management systems and legal regulations separately. Therefore, a first step was the design of an comprehensive proposal between the legislation and the standards on Good Manufacturing Practices of the cosmetic sector in Colombia; through the identification, comparison, combination, incorporation and merging of the requirements. The content of the proposal was evaluated by experts and as a final result the verification guide was produced.