To analyze the effects of confinement on the level of stress in submariners. a systematic review was carried out, whose search was carried out in the MEDLINE, Cochrane, Web of Science, SCOPUS and Embase databases in (June 2023), following the PRISMA 2020 guidelines. The search equations were prepared, with the descriptors “submariners” and “Stress” or “Stress, Psychological”, “Psychological Distress”, “Occupational Stress”, “Stress Disorders”, “Stresses Tests”, “Perceived Stress”, with synonyms. In the databases: Pubmed, Cochrane, Web of Science, SCOPUS and Embase. Studies were included that sampled submariners, whose results were indicators of stress. From a total of 1,905 articles, 8 eight studies were included in the review. Different stress assessment instruments were found, such as questionnaires, inventories, scales, ECG; salivary cortisol and nocturnal urinary excretion of free cortisol. The stressors that stood out with confinement in submariners were post-traumatic, occupational, organizational, psychosocial stress and general stressors in the individual's life.