The results of this paper are determined by the guidelines and regulations applicable to teleworking in Colombia in terms of occupational health and safety, to the design of the Occupational Health and Safety Model for autonomous teleworking, and to the structuring and validation of the Maturity of the Occupational Health and Safety Management System (ema), Quality of Life (CoL), and Working Conditions (wc) instruments. For the development of the Model, the following categories were analyzed: advantages and disadvantages of teleworking, teleworking modalities, worker conditions, environmental conditions, conditions of the tasks, change management, leadership, and quality of life. Statistical validations were performed on each proposed instrument, such as internal consistency, factor analysis, and component analysis. In the proposed Model, the employer or contractor must address the prevention of accidents and occupational diseases and the protection and promotion of the health of workers and/or contractors through the implementation, maintenance, and continuous improvement of a management system with principles based on the pdca cycle (Plan, Do, Check, and Act).

Research in Occupational Health and Safety for Autonomous Teleworking in Colombia was carried out under the management systems approach based on the Colombian Technical Standard (Norma Técnica Colombiana, NTC) ISO 45001:2018 of Management System (MS) in Occupational Safety and Health (OSH) and Decree 1072 of 2015 (Chapter 6 of MS OSH and Chapter 5 of Teleworking). A bibliographic review of research on the subject under study was carried out in 10 databases: Science Direct, VHL, Scopus, Scielo, EBSCO, IEEE, Redalyc, Springer, Latindex and academic Google, using the following key terms for the search in Spanish and English: Teleworking, Occupational Health and Safety, Occupational Health, Teleworkers, Teleworking, telecommuting, Safety and Health at Work, occupational health and teleworker; which resulted in the finding of 60 articles on research in the subject in the following countries: Argentina, Brazil, Chile, Australia, Belgium, Canada, Slovakia, Spain, United States, Estonia, India, Japan, Malaysia, New Zealand, Netherlands, Portugal and United Kingdom. The articles analyzed were organized into 14 categories to determine common and relevant aspects in the literature reviewed on teleworking